I’m not hypermobile - could I still have EDS?
Hypermobile Ehlers-Danlos Syndrome (hEDS) is one of the most challenging conditions to diagnose, and here’s why: there’s no genetic test for hEDS, and not everyone with the condition is hypermobile or shows “classic” symptoms.
However, after working with countless patients dealing with dysautonomia and suspected EDS, we’ve noticed some unmistakable patterns. One surprising clue? The activities you’re naturally drawn to. Gymnasts, dancers, cheerleaders, and ballerinas often have EDS. Male patients often have a natural athletic grace and excel in sports like baseball, swimming, or basketball. These patients are also more prone to chronic injuries from physical trauma—think falls or car accidents—and their recovery is often slower.
EDS patients are often the ones who react poorly to medications. If there’s a side effect or a weird reaction to be had, they’re likely to experience it. Many also report a history of frequent childhood illnesses, GI issues (bloating, acid reflux, IBS, gastroparesis), and food sensitivities.
EDS patients commonly suffer from Mast Cell Activation Syndrome (MCAS). This condition makes mast cells hypersensitive, leading to exaggerated immune responses like histamine release that trigger inflammation and discomfort. They’re also prone to Postural Orthostatic Tachycardia Syndrome (POTS), a condition where standing causes heart rate spikes due to autonomic nervous system dysfunction.
Put simply, EDS is more than a diagnosis—it’s a pattern of symptoms and experiences. And the better we understand these connections, the better equipped we are to help those with this complex condition.